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The protection effect and mechanism of hyperbaric oxygen therapy in rat brain with traumatic injury

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Abstract Background The aim of this study was to investigate the efficacy of hyperbaric oxygen in secondary brain injury after trauma and its mechanism in a rat model. Material/Methods A rat model of TBI was constructed using the modified Feeney’s free-fall method,...

Hyperbaric oxygen therapy: A new look on treating stroke and traumatic brain injury

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Abstract Although hyperbaric oxygen therapy (HBOT) is common as a treatment for injuries, this study aimed to research the ability of HBOT in preconditioning to diminish any potential damage. The hypothesis stated that HBOT preconditioning alleviated the death of...

A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Abstract Object: Preclinical and clinical investigations indicate that the positive effect of hyperbaric oxygen (HBO2) for severe traumatic brain injury (TBI) occurs after rather than during treatment. The brain appears better able to use baseline O2 levels following...

Hyperbaric oxygen alleviates the activation of NLRP‑3‑inflammasomes in traumatic brain injury

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Abstract Growing evidence has demonstrated that the nucleotide‑binding oligomerization domain‑like receptor family pyrin domain containing 3 (NLRP‑3) inflammasome‑mediated inflammatory pathways have been involved in the secondary injury of traumatic brain injury...

Hyperbaric Evaluation and Treatment Of Intracranial Abscess

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Summary A paper examining the usage of Hyperbaric Oxygen therapy for Intracranial Abscess, concluding that hyperbaric therapy has provided clinicians with an effective, non-invasive therapeutic option for patients with intracranial abscesses. Link to...

Hyperbaric Oxygen Alleviates Secondary Brain Injury After Trauma Through Inhibition of TLR4/NF-κB Signaling Pathway

by Sharon Kuttner | Jul 29, 2020 | TBI and Brain Condition Research

Abstract Background: The aim of this study was to investigate the efficacy of hyperbaric oxygen in secondary brain injury after trauma and its mechanism in a rat model. Material/methods: A rat model of TBI was constructed using the modified Feeney’s free-fall...
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